lenbilen

Europe allows use of Merckvectin and Pfizermectin, why is U.S. not?

The EU’s drug watchdog on November 19 backed Merck’s anti-COVID pill for emergency use ahead of its formal authorization and started reviewing Pfizer’s antiviral treatment as cases soar across Europe.

The two pills by the US pharma giants represent a potentially groundbreaking step in the fight against coronavirus as studies show they cut the risk of hospitalization and death in high-risk patients.

The European Medicines Agency (EMA) said that while the Merck pill was not yet approved, it had “issued advice” so that individual countries in the 27-nation EU could decide whether to use it in case of a surge in infections.

The EU’s drug regulator on Dec 16 allowed member states to use Pfizer’s new COVID pill ahead of its formal approval, as an emergency measure to curb an Omicron-fuelled wave.

Pills like those by US pharma giant Pfizer and rival Merck have been hailed as groundbreaking because they do not need to be injected or taken intravenously, making them more accessible.

Pfizer said this week that its Paxlovid pill reduced hospitalisations and deaths in vulnerable people by almost 90 percent.

“The medicine, which is not yet authorised in the EU, can be used to treat adults with COVID-19 who do not require supplemental oxygen and who are at increased risk of progressing to severe disease,” the EMA said in a statement.

“EMA issued this advice to support national authorities who may decide on possible early use of the medicine… for example in emergency use settings, in the light of rising rates of infection and deaths due to COVID-19 across the EU.”

Merck’s pill decreases the ability of the coronavirus to multiply by increasing the number of mutations in its genetic material (or RNA).

The Pfizer pill uses a different method, belonging to a class of antivirals called “protease inhibitors”, which block the action of an enzyme that is critical to viral replication.

It is a combination of a new molecule, PF-07321332, and HIV antiviral ritonavir.

Europe has been searching for whatever methods it can to curb a fourth wave of COVID cases that has already prompted several countries to tighten restrictions.

Why not approve Ivermectin?

When a new epidemic breaks out, one for which there is no approved medication available that will cure the patient it has always been the aim of the medical community to see if there are any approved drugs that can be repurposed to cure the patient, because it takes too long to develop brand new drugs.

When the COVID-19 pandemic broke out there was a wild scramble to see what other drugs were available, most of it in other countries. One such effort, in Marseille, France, by a Muslim doctor caught the attention of then President Trump, and he started promoting it. It involved Hydrochloroquine, Zinc and Azithromycine, and it worked remarkably well when taken early, people were cured in 5 days, but it had one fatal flaw, the main drug is generic, and therefore the medical-industrial complex could not make any money on it, so no studies in the U.S.A could be performed by it and so, it could not be approved. Plus, it had been promoted by Trump, and he was no medical expert. Many countries with limited medical budgets called on its wide use as an early treatment with good results, the death rate of these, mostly developing countries was substantially lower than the advanced countries. Here is some early evidence.

The sub-Saharan countries that are plagued by river blindness had almost no COVID cases early during the pandemic, but no- one noticed. It turns out that in those countries they are using Ivermectin to prevent river blindness. This also blocks COVID-19, and so, Ivermectin was inadvertently repurposed. How successful is it? The data is here. India and Indonesia have drastically reduced their COVID-19 cases by the use of Ivermectin, results here. Japan reducrd their COVID-cases by 99%, see here.

How well does Ivermectin fare compared to vaccination? Let’s check 3 nations, all tropical: Covid-19, Ivermectin compared to Vaccination. 3 nations: Haiti, Dominican Republic and Singapore.

. it works the same way as IverThe results speaks for themselves, that is for everybody except NIH, CDC and FDA. To protect their investment in COVID-19 disease management Pfizer is coming out with a pill, PF-07321332 which has been dubbed Pfizermectin by the social media, and for good reason, it works the same way as Ivermectin, but the molecule used is quite different. It is more specifically targeted at COVID-19, delta variant, and as such is even more efficient than Ivermectin, but Ivermectin is more broadband, and may work well against all future mutations of the virus and even against the next pandemic in the COVID family. The great advantage of the Pfizer pill is that it is expensive and as such will be approved lickety-split,, whereas the true cost in Africa for the Ivermectin pill is 6 cents.

Anyhow, here is Dr, John Campbell with the best presentation of how Ivermectin works I have seen. It has many scientific references.

December 17, read through the Holy Bible in a year.

Revelation 9. By now we are deep into the last half of the tribulation, the fifth trumpet sounded and the locusts from the bottomless pit are released. Then the sixth trumpet sounded, featuring the angels from the Euphrates doing horrendous deeds. An army of two hundred million mounted troops were released to kill a third of mankind. At the time of the Apostle John the total world population was about 250 million!

Haggai 2 describes the coming glory of God’s house, but the people were defiled. Nevertheless God promised a future blessing with Zerubbabel chosen to be like God’s signet ring.

December 16, read through the Holy Bible in a year.

Revelation 8 describes the precursors to the great tribulation with the opening of the seventh seal and the sounding of the trumpets. It begins with an earthquake. First Trumpet: Vegetation Struck, Second Trumpet: The Seas Struck, Third Trumpet: The Waters Struck, Fourth Trumpet: The Heavens Struck; one ecological disaster after another.

Haggai 1 is about having the right priorities. God had commanded the inhabitants of Jerusalem to rebuild His house. When pointed out their wrongful ways the people obeyed.

December 15, read through the Holy Bible in a year.

Revelation 7. The apostle John saw angels telling of the 144 thousand sealed of Israel, and then saw a multitude that came out of the Great Tribulation singing praises such as “Amen: Blessing, and glory, and wisdom, and thanksgiving, and honour, and power, and might, be unto our God for ever and ever. Amen.”

Proverbs 28, more proverbs of Solomon. Wisdom is important, so here are many more proverbs about wisdom and righteousness, and the consequences of the lack thereof.

December 14, read through the Holy Bible in a year.

Revelation 6. The first six seals are opened. First Seal: The rider on a white horse. He represents the conqueror or the Catholic Church. Second Seal: The rider on a red horse. He represents conflict on earth or the powers of humanism, secularism, communism and socialism. Third Seal: The rider on the black horse. He represents scarcity on earth or the results of unrestrained capitalism. Fourth Seal: The rider on the green horse. He represents mass death on earth or the religion/state power of Islam. Fifth Seal: The Cry of the Martyrs. “It was said unto them, that they should rest yet for a little season, until their fellow servants also and their brethren, that should be killed as they were, should be fulfilled.” Then comes the Sixth Seal with the Great Earthquake. It is at this time I place the rapture of the believers. We are living in the time of the first five seals already being opened. Read all the Old Testament references and see if it makes sense to you. This is but one interpretation since Revelation is deliberately veiled, lest we would go ahead on our own trying to make human sense out of it.

Zephaniah 3. Jerusalem was full of wickedness but there remained a faithful remnant and they would rejoice in God’s faithfulness, restoring His people.

December 13, read through the Holy Bible in a year.

Revelation 5. Worship is continued in heaven and the Apostle John saw a scroll. Nobody but the Lamb was worthy to take and open the scroll with seven seals. All present broke out in praise, singing a new song, saying, “Thou art worthy to take the book, and to open the seals thereof: for thou wast slain, and hast redeemed us to God by thy blood” and “Blessing, and honour, and glory, and power, be unto him that sitteth upon the throne, and unto the Lamb for ever and ever. And the four beasts said, Amen. And the four and twenty elders fell down and worshipped him that liveth for ever and ever.”

Zephaniah 1 is a prophecy of the Great Day of the LORD.

Zephaniah 2 is a call to repentance and a prophecy of judgment on many nations.

December 12, read through the Holy Bible in a year.

Revelation 4. The Apostle John was shown the throne room of Heaven. Someone was sitting on the throne. A rainbow was over it, 24 elders were around it, in the front were seven lamps, representing the seven-fold spirit of God. Around it were also four creatures, one like a lion, representing Jesus as king (Matthew), one like an ox representing Jesus as a servant (Mark), one with the face of man representing the humanity of Christ (Luke), and the fourth like an eagle representing Jesus is God (John). All sang or said praises, a true worship.

Proverbs 27. More Proverbs of Solomon. This chapter deals with the future, and what to do about it today. One notable quote: “Iron sharpeneth iron; so a man sharpeneth the countenance of his friend.”

Psalm 148: Let all creation praise the LORD!

December 11, read through the Holy Bible in a year.

Revelation 3 ends the message to the seven churches: To Sardis, the church that claimed to be alive, but in God’s eyes was dead; to Philadelphia, the church that kept its faith, and as a reward will be kept from the hour of trial that is coming; and finally to the church of Laodicea, the church that thought it had it all figured out and prospered, when in reality it had nothing. These can be seen as seven historical churches, which they were, but also as seven types of churches as they exist today and through history. They can also be taken as seven states of the individual believer. However you take it, there is something in it for every believer, even today.

In Habakkuk 3 is recorded Habakkuk’s prayer, a hymn of faith.

Psalm 147 is a great Psalm of praising God for His protection and creation, for His care and power, for His provisions, wisdom and His word. It ends with praise to the LORD for His special attention to Israel.

The connection between Viagra and Alzheimer. Could there be something else, and what has this to do with COVID-19?

A large medical study of seniors, both Viagra users and non users (7.2 million seniors medical records were scanned for six years by the Cleveland Clinic) and they found that Viagra users were 69% less likely to develop Alzheimer disease. This was interesting. Did they find anything else? Less Cancer, less Parkinson’s disease?

Could there be something else that made a difference? Viagra itself was developed to be a blood pressure lowering drug by expanding the blood vessels. During the early trials they found that it had some unexpected side effects. For some, the side effects were desirable, so they repurposed the drug, and Pfizer racked up about 15 Billion dollars in sales until the patent expired in 2020. It is now generic under the name sildenafil. There is only one problem with this. To repurpose a drug, in this case against Alzheimer you have to have a control group that is not aware that they are given a placebo, which is not possible in this case. Plus it is now generic, so there is no interest in doing a double blind study for economic reasons, it no longer fits the medical industry’s business model.

Many years ago I saw a nicely framed plug for flossing in my dentist’s office. It said: People who floss every day live on average seven years longer. This may very well be true, but could it also be because people who floss take care of themselves in many other ways?

A long time ago there was a study that established a strong correlation between circumcision and prostate cancer. People who were not circumcised had a much higher incident of prostate cancer, case closed, get circumcised. There was only one problem with the study: It was taken mostly in Minnesota with a large Scandinavian population. Scandinavians do not get circumcised as a rule, and they are genetically much more prone to get prostate cancer than other people. When the genetic variations are taken out, there is no difference between circumcision, non circumcision and cancer.

Which brings me to COVID-19 and why more pigmented people are more likely to suffer, even die from COVID-19. The first excuse is that they get an inferior health care because we are a deeply racist society. There are a couple of other possibilities. An Indonesian study showed a strong correlation between Vitamin D levels and fatal outcome for older people with COVID-19. If the level was below 27 ng/ml the death rate was over 80%, if the level was over 31 ng/ml the death rate was less than 10%. See: https://lenbilen.com/2020/12/27/vitamin-d-as-covid-19-fighter-a-most-important-virus-fighter/

Another possibility is there are genetic differences between people of dark complexion and pale-skinned people. It is through genetic differences we determine our ancestry, it has become widely popular, so it is not in and of itself racist to look into one’s roots. It turns out that the rate of COVID-19 in equatorial Africa is much lower than in U.S. In Africa there was a debilitating illness called river blindness. The parasite killer Ivermectin, originally developed against parasites in horses and as heart worm killer in dogs proved effective against river blindness, and so it became widely distibuted in Central Africa. The countries that use Ivermectin have around one tenth of the cases than the countries of North and Southern Africa. It seems that Ivermectin had been inadvertently repurposed to fight COVID-19. See: https://lenbilen.com/2020/12/27/vitamin-d-as-covid-19-fighter-a-most-important-virus-fighter/

To test this hypothesis Indonesia, India and Japan did introduced Ivermectin as the primary early prophylactic and therapeutic COVID-19 fighter. The results are startling, Indonesia has seen new cases drop 99.5% and deahs drop 99.4% since the peak before introduction of Ivermectin. The corresponding numbers for India are 98% and 93.3%, but in Uttar Pradesh and Delhi the results are much better. In Japan the cases are down 99.5% and deaths are down 98.4%.

Can the U.S. achieve similar successes by repurpose Ivermectin to fight COVID-19? It is a strong virus killer, and it is more broadband than the mRNA vaccines. The vaccines work too as a Prophylactic Therapeutic for a season, but is what they call leaky insofar that they are more specific and make possible an occasional vaccine resistant mutation to develop, and so a vaccine booster variant has to be developed and distributed, thus satisfying the medical industry’s business model, first do not cure the patient, but maintain stable control and assure the patient of a long life of dependency.

The other buisness model advocared by the medical doctors and nurses is that they really want to cure the patient. Ivermectin will go a long way to achieve that goal. Just think, reducing COVID hospitalizations and deaths by a modest 90% in about seven weeks after Ivermectin is fully approved would change things.

What are we waiting for?

December 10, read through the Holy Bible in a year.

Revelation 2:12-29 continues the message to the seven churches, church three and four: Pergamos, a church that looked good but compromised itself, and the church of Thyatira, a corrupted church, but with hope of repentance. These can be seen as seven historical churches, which they were, but also as seven types of churches as they exist today and through history. They can also be taken as seven states of the individual believer. Whichever way you take it, there is something in it for every believer, even today.

Habakkuk 1 begins with the prophet’s first complaint and the LORD’s reply. After that the prophet poured out his second complaint.

Habakkuk 2. The LORD answered the prophet to his second complaint. It contains this gem, just as valid today as it was then: “The just shall live by his faith“. On the other hand God promised more woe to the wicked.