This pre-publication paper, not yet peer reviewed; https://www.medrxiv.org/content/10.1101/2022.01.22.22269660v1#disqus_thread is eye opening.
The take home from this pre-publication study is that there seems to be no difference in the probability of getting the Omicron variety of COVID or the Delta variety if you are unvaccinated, but the risk for being infected doubles if you are double vaccinated, and triple if you are also boosted. This means that the vaccines are less effective if you have had a booster shot for the Omicron variant. The Covid pandemic has moved from a pandemic of the unvaccinated to a pandemic of the vaccinated. My hopethesis is that the vaccines are too specific to work for a heavily mutated COVID such as the Omicron variety. We need a more broadband vaccine. Lucky for us they have changed the definition of what a vaccine is to include substances that lessen the impact of a disease, as prophylactic and therapeutic. With that definition there is already such a vaccine. It is called Ivermectin.
Let us test this hypothesis comparing the experience of U.S. and Nigeria. Since the start of the pandemic the U.S. has had 221,892 cases per million and 2,689 deaths per million people. By contrast, Nigeria has had 1,180 cases per million and 15 deaths per million, or about 0.53 percent of the cases and 1.27% of the deaths per million people.
How can that be? United states has the best medical system in the world, spending about 20% of GNP on medical care, Nigeria spends about 4% of their GNP on medical care. The median age for people in u.s is about 38.4 years, for Nigeria the median age is 18.4 years. The expected death risk for U.S.is about 5 times larger thanks to the age factor, so this makes up part of the difference. But the difference is far greater, so there must be something else. I am willing to accept that Nigeria has under-reported the number of cases, but the difference is much larger than can be explained this way. In addition Nigeria has one of the lowest vaccination rates in the world, less than 3%.
There is one better hypothesis, Nigeria has a great problem with River Blindness, a parasite on the skin that causes blindness if not treated. There is medication, given to all without cost, and it does the job. This medication is Ivermectin, and thanks to that the COVID cases are lower by a factor of 20, age-adjusted. Recently there has been a small study in Nigeria that seem to suggest that if you combine Ivermectin with HCQ and Zinc and Azithromycin, the results are even better. The results are presented here.
Want to save over a thousand deaths a day in U.S. alone? Switch immediately from vaccine only therapy to immediately allow Ivermectin and HydroxyChloroquine to be sold over the counter. The deaths from Ivermectin are only 15/ year worldwide and for Hydroxy Chloroquine 65/year worldwide, far less than say Tylenol, while the deaths from the vaccines are over 20,000 in the first year. The vaccines are great for people over 45, but for the younger generation the death risk outweighs the benefits.