In Indiatoday Prabhash K Dutta, New Delhi wrote in June 7, 2021:
Remember Donald Trump-touted hydroxychloroquine? Study in India backs it as Covid-19 cure.
Hydroxychloroquine, the malaria drug touted as a magical Covid-19 cure by former US President Donald Trump last year, has been found effective in a prophylactic study published in a prophylactic study published in the Journal of The Association of Physicians of India (JAPI) last week..
The study showed that hydroxychloroquine, popularly known as HCQ, could prevent SARS-CoV-2 infection in varying degrees depending on its dosing regimen. The highest prevention rate of 72 per cent was found among those given hydroxychloroquine over six weeks or a longer duration.
The study said, “[W]hen adjusted for other risk factors, HCQ dose as per government recommendations, 2-3, 4-5, 6 or more weeks reduced the probability of Covid positivity by 34 per cent, 48 per cent and 72 per cent.”
The study was conducted May-September last year when HCQ was still part of the Union health ministry’s recommendation in treatment protocol for Covid-19, and it began against the backdrop of contesting claims made by authorities and experts including Donald Trump and his advisor Dr Anthony Fauci, the US’s top infectious disease expert.
In March 2020, Donald Trump declared that hydroxichloroquine was a “game changer” drug in the fight against Covid-19. Dr Fauci dismissed the claim citing lack of study and evidence. Despite Fauci’s counter-positioning, Trump continued to be vocal about taking HCQ as prophylactic drug.
Incidentally, the Union health ministry on June 6 dropped hydroxychloroquine from Covid-19 treatment protocol. In its nine-page guidelines released on Sunday (June 6) by the directorate of health services, hydroxychloroquine, ivermectin and favipiravir find no mention.
The government’s decision came on the back of criticism by experts who pointed out a lack of study-based evidence to recommend hydroxychloroquine in Covid-19 cases. The government’s revised guidelines, however, contradicts the recommendations made by the Indian Council of Medical Research as released on May 17.
The ICMR guidelines prescribed the use of hydroxychloroquine in mild cases of Covid-19.
The authors of this prophylactic (relating to prevention of a disease) study said that this “is the largest multicenter study on HCQ prophylaxis on HCWs (healthcare workers), covering over 12,000 HCWs at the risk of Covid-19”.
The study was conducted in May-September last year across 44 hospitals in 17 states involving hundreds of doctors, who received doses of hydroxychloroquine.
One of the co-authors of the study, Dr Raj Kamal Choudhry said, “In the 1985-86 edition of Harrison’s Principles of Internal Medicine [a highly recommended book for students studying medicine in medical colleges], Dr. Fauci wrote that HCQ worked an anti-viral agent despite being an anti-malarial drug. There was no Covid-19 back then, but HCQ’s anti-viral properties were already well known.”
Dr Raj Kamal Choudhry, who was the nodal officer for the prophylaxis study of HCQ in Bihar’s Bhagalpur medical college, said, “We had given about 2,700 doctors and paramedical staff, laundry and kitchen people the prophylaxis of HCQs in the dose of HCQs 400 mg 1×2 for first day then 1 tab daily for 4 days.”
“We did not give to those who had palpitations and had QT prolongation [a measure of heart ailment]. Those who took this drug did not have Covid excepting 5 and 6. The effect was tremendous. Later, we gave this drug to all who had mild cases. Only those patients who were in ICU were not given.”
“Of 2,700 people who were given HCQs, 700 were doctors. Only five or six got infected with SARS-CoV-2 in Bhagalpur but none developed serious complications, and nobody died of Covid-19,” Dr Raj Kamal Choudhry told Indiatoday.in.
The evidence is piling up. There has been numerous, over 50 studies like this showing that HCQ is effective, both as prophylactic, and as an early cure. Yoo bad that the medical bureaucracy considered it more important to get rid of Donald Trump than to save over 100,000 lives in U.S. alone.
In addition HCQ is too cheap and generic to warrant a double blind study.
The other medication that may be as effective, and save lives is Ivermectin, an anti-parasite drug used to treat horses and other farm animals. You can buy it at Tractor Supply, so I have been told. I do not know proper dosages, but if done properly, it is safe for humans when treating parasitic infections. It also is too cheap for the medical community to take seriously.
One more thing, make sure you take supplemental Vitamin D3 (I take 5000 IU/day). An Indonesian study found that the death rate went from 95% if the values were less than 19 nanograms/milliliter to less than 5% if the D3 values were over 31 nanograms/milliliter. The study was made in Covid patients over 65 years old.